Man being examined for glaucoma

AZOPT® Suspension

AZOPT® Suspension AZOPT® Suspension AZOPT® Suspension
AZOPT® Suspension eyedrops AZOPT® Suspension eyedrops AZOPT® Suspension eyedrops
OPENINGS® Patient Support Program OPENINGS® Patient Support Program OPENINGS® Patient Support Program

OPENINGS® Patient Support Program

A little help can go a long way. Join the OPENINGS® Patient Support Program now for helpful information, tools, and savings for eligible patients* that can help making staying on a track a bit easier. Enrolling is free and easy.

Learn More

*This offer is not valid for patients who are enrolled in Medicare Part D, Medicaid, Medigap, VA, DOD, Tricare, or any other government-run or government-sponsored health care program with a pharmacy benefit. If you are not eligible for the Program Savings Card, you can still enjoy all the other benefits of the OPENINGS® Patient Support Program.

Important information about AZOPT® (brinzolamide ophthalmic suspension) 1%

AZOPT® Suspension is a carbonic anhydrase inhibitor (CAI) indicated in the treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.

Dosage and Administration

The recommended dose is one drop of AZOPT® Suspension in the affected eye(s) three times daily. If more than one topical ophthalmic drug is being used, the drugs should be administered at least ten (10) minutes apart


AZOPT® Suspension is contraindicated in patients who are hypersensitive to any component of this product.

Warnings and Precautions

Sulfonamide Hypersensitivity Reactions -AZOPT® Suspension is a sulfonamide and although administered topically it is absorbed systemically. The same types of adverse reactions that are attributable to sulfonamides may occur with topical administration of AZOPT® Suspension. Fatalities have occurred, although rarely, due to severe reactions to sulfonamides. Sensitization may recur when a sulfonamide is re-administered irrespective of the route of administration. If signs of serious reactions or hypersensitivity occur, discontinue the use.

Corneal Endothelium-Carbonic anhydrase activity has been observed in both the cytoplasm and around the plasma membranes of the corneal endothelium. There is an increased potential for developing corneal edema in patients with low endothelial cell counts. Caution should be used when prescribing AZOPT® Suspension to this group of patients.

Severe Renal Impairment -AZOPT® Suspension has not been studied in patients with severe renal impairment (CrCl < 30 mL/min). Because AZOPT® Suspension and its metabolite are excreted predominantly by the kidney, AZOPT® Suspension is not recommended in such patients.

Acute Angle-Closure Glaucoma -The management of patients with acute angle-closure glaucoma requires therapeutic interventions in addition to ocular hypotensive agents.
AZOPT® Suspension has not been studied in patients with acute angle-closure glaucoma.

Contact Lens Wear - - The preservative in AZOPT® Suspension, benzalkonium chloride, may be absorbed by soft contact lenses. Contact lenses should be removed during instillation, but may be reinserted 15 minutes after instillation.

Adverse Reactions

In clinical studies of AZOPT® Suspension, the most frequently reported adverse events reported in 5-10% of patients were blurred vision and bitter, sour or unusual taste. Adverse events occurring in 1-5% of patients were blepharitis,dermatitis, dry eye, foreign body sensation, headache, hyperemia, ocular discharge, ocular discomfort, ocular keratitis, ocular pain, ocular pruritus and rhinitis.

Drug Interactions

Oral Carbonic Anhydrase Inhibitors - There is a potential for an additive effect on the known systemic effects of carbonic anhydrase inhibition in patients receiving an oral CAI and AZOPT® Suspension. The concomitant administration of AZOPT® Suspension and oral CAIs is not recommended.

High-Dose Salicylate Therapy - In patients treated with oral CAIs, rare instances of acidbase alterations have occurred with high-dose salicylate therapy. Therefore, the potential for such drug interactions should be considered in patients receiving AZOPT® Suspension.

Click here for full prescribing information for AZOPT® Suspension

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit, or call 1-800-FDA-1088.

See More +
See Less -